{"id":26877,"date":"2024-12-10T10:08:33","date_gmt":"2024-12-10T02:08:33","guid":{"rendered":"https:\/\/ljdevice.com.tw\/?p=26877\/"},"modified":"2024-12-10T10:08:33","modified_gmt":"2024-12-10T02:08:33","slug":"researchers-develop-wearable-patch-monitors-blood-pressure-anywhere","status":"publish","type":"post","link":"https:\/\/ljdevice.com.tw\/en\/researchers-develop-wearable-patch-monitors-blood-pressure-anywhere\/","title":{"rendered":"Researchers Develop Wearable Patch That Monitors Blood Pressure Anywhere"},"content":{"rendered":"

\"\"<\/p>\n

A new wearable ultrasound patch from UC San Diego provides continuous, noninvasive blood pressure monitoring, extensively tested and clinically validated on over 100 patients.<\/strong><\/p>\n

Researchers at the University of California San Diego have developed a new wearable ultrasound patch for continuous and noninvasive blood pressure monitoring. The device is the first wearable ultrasound blood pressure sensor to undergo rigorous and comprehensive clinical validation on over 100 patients.<\/p>\n

Recently published in\u00a0Nature Biomedical Engineering<\/em>, this technology could potentially improve the quality of cardiovascular health monitoring both in clinical settings and at home.<\/p>\n

\u201cTraditional blood pressure measurements with a cuff, which are limited to providing one-time blood pressure values, can miss critical patterns. Our wearable patch offers a continuous stream of blood pressure waveform data, allowing it to reveal detailed trends in blood pressure fluctuations,\u201d said study co-first author Sai Zhou, who recently graduated with his Ph.D. in materials science and engineering from the UC San Diego Jacobs School of Engineering.<\/p>\n

The patch is a soft and stretchy device about the size of a postage stamp that adheres to the skin. When worn on the forearm, it offers precise, real-time readings of blood pressure deep within the body. The patch is made of a silicone elastomer that houses an array of small piezoelectric transducers sandwiched between stretchable copper electrodes. The transducers transmit and receive ultrasound waves that track changes in the diameter of blood vessels, which are then converted into blood pressure values.<\/p>\n

\"Wearable<\/a>
This small, stretchy skin patch uses ultrasound to continuously monitor blood pressure deep inside the body. A comprehensive clinical validation on 117 subjects, including patients in the intensive care unit, has demonstrated its potential as a simpler and more reliable alternative to current clinical methods for monitoring blood pressure. Credit: David Baillot\/UC San Diego Jacobs School of Engineerin<\/figcaption><\/figure>\n

Advancements in Wearable Ultrasound Technology<\/h4>\n

The wearable ultrasound patch builds upon an\u00a0earlier prototype<\/u><\/a>\u00a0pioneered by the lab of Sheng Xu, a professor in the Aiiso Yufeng Li Family Department of Chemical and Nano Engineering at UC San Diego. Researchers re-engineered the patch with two key improvements to enhance its performance for continuous blood pressure monitoring. First, they packed the piezoelectric transducers closer together, enabling them to provide wider coverage so they could better target smaller arteries, such as the brachial and radial arteries, which are more clinically relevant. Second, they added a backing layer to dampen redundant vibrations from the transducers, resulting in improved signal clarity and tracking\u00a0accuracy<\/span>\u00a0of arterial walls.<\/p>\n

In tests, the device produced results comparable to those of a blood pressure cuff and another clinical device called an arterial line, which is a sensor inserted into an artery to continuously monitor blood pressure. While the arterial line is the gold standard for blood pressure measurement in intensive care units and operating rooms, it is highly invasive, limits patient mobility, and can cause pain or discomfort. The patch provides a simpler and more reliable alternative, as shown in validation tests conducted on patients undergoing arterial line procedures in cardiac catheterization laboratories and intensive care units.<\/p>\n

\"Sai<\/a>
Sai Zhou, one of the study\u2019s co-first authors, holds the re-engineered wearable ultrasound patch. Credit: UC San Diego Jacobs School of Engineering<\/figcaption><\/figure>\n

Comprehensive Clinical Validation and Performance<\/h4>\n

Researchers conducted extensive tests to validate the patch\u2019s safety and accuracy. A total of 117 subjects participated in studies that evaluated blood pressure across a wide range of activities and settings. In one set of tests, seven participants wore the patch during daily activities such as cycling, raising an arm or leg, performing mental arithmetic, meditating, eating meals, and consuming energy drinks. In a larger cohort of 85 subjects, the patch was tested during changes in posture, such as transitioning from sitting to standing. Results from the patch closely matched those from blood pressure cuffs in all tests.<\/p>\n

The patch\u2019s ability to continuously monitor blood pressure was evaluated in 21 patients in a cardiac catheterization laboratory and four patients who were admitted to the intensive care unit after surgery. Measurements from the patch agreed closely with results from the arterial line, showcasing its potential as a noninvasive alternative.<\/p>\n

\u201cA big advance of this work is how thoroughly we validated this technology, thanks to the work of our medical collaborators,\u201d said Xu. \u201cBlood pressure can be all over the place depending on factors like white coat syndrome, masked hypertension, daily activities or use of medication, which makes it tricky to get an accurate diagnosis or manage treatment. That\u2019s why it was so important for us to test this device in a wide variety of real-world and clinical settings. Many studies on wearable devices skip these steps during development, but we made sure to cover it all.\u201d<\/p>\n

\"Wearable<\/a>
This small, stretchy skin patch uses ultrasound to continuously monitor blood pressure deep inside the body. A comprehensive clinical validation on 117 subjects, including patients in the intensive care unit, has demonstrated its potential as a simpler and more reliable alternative to current clinical methods for monitoring blood pressure. Credit: David Baillot\/UC San Diego Jacobs School of Engineering<\/figcaption><\/figure>\n

Future Directions and Improvements<\/h4>\n

The research team is preparing for large-scale clinical trials and plans to integrate\u00a0machine learning<\/span>\u00a0to further improve the device\u2019s capabilities. Efforts are also underway to validate a wireless, battery-powered version for long-term use and seamless integration with existing hospital systems.<\/p>\n

Reference: \u201cClinical validation of a wearable ultrasound sensor of blood pressure\u201d by Sai Zhou, Geonho Park, Katherine Longardner, Muyang Lin, Baiyan Qi, Xinyi Yang, Xiaoxiang Gao, Hao Huang, Xiangjun Chen, Yizhou Bian, Hongjie Hu, Ray S. Wu, Wentong Yue, Mohan Li, Chengchangfeng Lu, Ruotao Wang, Siyu Qin, Esra Tasali, Theodore Karrison, Isac Thomas, Benjamin Smarr, Erik B. Kistler, Belal Al Khiami, Irene Litvan and Sheng Xu, 20 November 2024,<\/p>\n

Source:Researchers Develop Wearable Patch That Monitors Blood Pressure Anywhere<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

December 2, 2024<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[609],"tags":[],"class_list":["post-26877","post","type-post","status-publish","format-standard","hentry","category-industrial-news"],"_links":{"self":[{"href":"https:\/\/ljdevice.com.tw\/en\/wp-json\/wp\/v2\/posts\/26877","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ljdevice.com.tw\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ljdevice.com.tw\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ljdevice.com.tw\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/ljdevice.com.tw\/en\/wp-json\/wp\/v2\/comments?post=26877"}],"version-history":[{"count":2,"href":"https:\/\/ljdevice.com.tw\/en\/wp-json\/wp\/v2\/posts\/26877\/revisions"}],"predecessor-version":[{"id":26879,"href":"https:\/\/ljdevice.com.tw\/en\/wp-json\/wp\/v2\/posts\/26877\/revisions\/26879"}],"wp:attachment":[{"href":"https:\/\/ljdevice.com.tw\/en\/wp-json\/wp\/v2\/media?parent=26877"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ljdevice.com.tw\/en\/wp-json\/wp\/v2\/categories?post=26877"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ljdevice.com.tw\/en\/wp-json\/wp\/v2\/tags?post=26877"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}